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Emergency angioplasty on June 19th - 56 year young woman, LDL was 150. 6 weeks on Simvastatin 40mg before bed, stopped all butter changed to Smart Balance, 80-100 oz water daily, lost 15 lbs, LDL is 54. WOW. On other medicines, so really can't tell if any side effects as associated with Simvastatin, but great results.
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They work to limit cholesterol levels by reducing the activity of HMG-CoA reductase, which is an enzyme that can create cholesterol in the liver.
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However, the NLA emphasizes that, in most cases, the risk of new onset diabetes is low and supports the FDA's conclusion that the cardiovascular benefits of statins outweigh these small increased risks.
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